Cutaneous T-cell lymphoma

Cutaneous T-cell lymphoma recovered with CDS

By: Dr. Jorge Ponce – Honduras, Kalcker Institute Master's Student

A 69-year-old female presented with progressive generalized weakness and new-onset cutaneous rashes that prompted initial evaluation at a local health center and subsequent referral to a general hospital for further work-up. Dermatologic assessment and skin biopsy were performed, and immunohistochemical analysis of the lesional tissue confirmed a diagnosis of cutaneous T‑cell lymphoma, establishing a neoplastic T‑cell infiltrate as the cause of her dermatosis. Staging investigations included a chest radiograph that demonstrated cardiomegaly consistent with grade 1 cardiomegaly, an important comorbidity to consider when planning systemic therapies and supportive care. Clinically, the combination of systemic symptoms such as weakness together with chronic or evolving cutaneous lesions should raise suspicion for a cutaneous lymphoma spectrum disorder, and the definitive diagnosis relies on histology supported by immunophenotyping, which in this case proved diagnostic.

Recovered with CDS and DMSO

Enema Protocol

Protocol C-10

Protocol K